My notebook screen is 14-inch with 1080p. I think it is recommended to adjust display settings to use GMS2 better on Windows if screen is 1080p, especially if less than 1080p.
On Windows ten/Display settings with 1920x1080 px resolution, i use " 125% " on Scale and layout. //This will give effect to all programs, not just GMS2, restart windows if no effect
On GMS2 i don't enable DPI override. It is 144 Raw DPI value.
I like this setting.
I think you can experiment on the percentage of "Scale and layout" on Windows/Display settings and/or also with DPI override settings on GMS2 Preferences/General Settings.
Edit: I use GML, not DnD. Maybe it is different with the layout if there are also buttons on the right side of the window.